Skip to main content
. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Pharm Res. 2014 Nov 13;32(5):1663–1675. doi: 10.1007/s11095-014-1565-2

Figure 1. Carboxylesterase activity in the blood and organs of wild-type, Ces1c +/− and Ces1c −/− mice.

Figure 1

The plasma and organs were incubated with (A) 1 mM 4-nitrophenyl acetate (4-NPA) (incubation time: 2min) or (B) 100 µM phospho-sulindac (P-S) (incubation time: 1h) in phosphate-buffered saline at 37°C, and the rate of hydrolysis was measured by spectrophotometry or HPLC.