Figure 2. Pharmacokinetic studies of phospho-sulindac in wild-type and Ces1c −/− mice.
Blood levels of phospho-sulindac (P-S) and sulindac in wild-type and Ces1c −/− mice after a single dose of (A) P-S (300mg/kg i.p.), (B) PLA-PEG P-S (50mg/kg, i.v.) and (C) Pluronic P123 P-S (50mg/kg, i.v.), respectively.