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. Author manuscript; available in PMC: 2015 Apr 2.
Published in final edited form as: Cell Rep. 2015 Mar 26;10(12):1982–1991. doi: 10.1016/j.celrep.2015.02.063

Figure 3. Role of ERβ repression in prostate tumorigenesis.

Figure 3

Ventral prostates of wild-type (control) and aged-matched Pten pc−/−mice were stained for (A) HIF-1α, (B) VEGF-A and (C) BMI-1 and analyzed by immunofluorescence microscopy. Scale bar, 50 µm. (D) Immunoblot showing the expression of HIF1α, VEGF-A and BMI-1 in PTEN-depleted (shPTEN) and control (shGFP) PNT1a cells. (E) Expression of VEGF-A and BMI-1 in ERβ expressing PTEN depleted cells (shPTEN-2+HA-ERβ) compared to PTEN depleted cells (shPTEN).