Table 2.
CPT performance by site for schizophrenia patients and healthy comparison subjects (HCS) (without age adjustment)
| Site 1 | Site 2 | Site 3 | Site 4 | Site 5 | All Sites | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCS | Patients | HCS | Patients | HCS | Patients | HCS | Patients | HCS | Patients | HCS | Patients | |
| DS-CPT | ||||||||||||
| N | 206 | 286 | 207 | 233 | 158 | 170 | 189 | 235 | 212 | 216 | 972 | 1140 |
| d’ | 2.41 (1.02) | 1.87 (0.94) | 1.97 (1.08) | 1.37 (0.93) | 2.22 (1.04) | 1.49 (0.99) | 2.57 (1.13) | 1.79 (1.01) | 2.42 (0.97) | 2.02 (1.06) | 2.32 (1.07) | 1.72 (1.01) |
| In beta | 0.84 (0.90) | 0.74 (0.90) | 0.52 (0.76) | 0.48 (0.68) | 0.75 (0.87) | 0.69 (0.74) | 1.22 (1.03) | 0.85 (0.73) | 1.08 (0.96) | 0.77 (0.91) | 0.88 (0.94) | 0.71 (0.81) |
| Hit rate | 0.74 (0.20) | 0.65 (0.21) | 0.70 (0.21) | 0.60 (0.21) | 0.71 (0.22) | 0.58 (0.24) | 0.72 (0.21) | 0.60 (0.23) | 0.72 (0.20) | 0.67 (0.23) | 0.72 (0.21) | 0.62 (0.23) |
| False alarm rate | 0.07 (0.07) | 0.11 (0.09) | 0.13 (0.13) | 0.18 (0.14) | 0.08 (0.06) | 0.14 (0.13) | 0.06 (0.07) | 0.09 (0.07) | 0.07 (0.08) | 0.11 (0.11) | 0.08 (0.09) | 0.12 (0.11) |
| RT hits (msec) | 503 (57) | 553 (80) | 504 (78) | 553 (79) | 517 (71) | 560 (93) | 516 (59) | 567 (82) | 511 (71) | 542 (80) | 510 (68) | 555 (82) |
| RT false alarms (msec) | 493 (82) | 527 (80) | 493 (82) | 534 (79) | 506 (79) | 526 (88) | 503 (92) | 537 (88) | 491 (83) | 506 (89) | 497 (84) | 527 (85) |
| CPT-IP 3-digit | ||||||||||||
| N | 220 | 290 | 202 | 236 | 174 | 207 | 191 | 236 | 212 | 221 | 999 | 1190 |
| d’ | 3.24 (0.81) | 2.23 (0.90) | 3.21 (0.85) | 2.19 (1.00) | 3.13 (1.01) | 1.86 (1.05) | 3.24 (0.80) | 2.14 (0.94) | 3.25 (0.87) | 2.39 (0.90) | 3.22 (0.87) | 2.17 (0.97) |
| Hit rate | 0.87 (0.12) | 0.69 (0.21) | 0.86 (0.14) | 0.69 (0.23) | 0.86 (0.17) | 0.63 (0.24) | 0.89 (0.12) | 0.69 (0.21) | 0.87 (0.14) | 0.73 (0.20) | 0.87 (0.14) | 0.68 (0.22) |
| False alarm rate | 0.04 (0.04) | 0.07 (0.07) | 0.04 (0.05) | 0.08 (0.08) | 0.05 (0.05) | 0.11 (0.10) | 0.05 (0.04) | 0.09 (0.08) | 0.04 (0.04) | 0.07 (0.07) | 0.04 (0.04) | 0.08 (0.08) |
| RT hits (msec) | 490 (65) | 555 (83) | 503 (71) | 563 (96) | 496 (76) | 563 (103) | 493 (72) | 549 (96) | 477 (72) | 532 (83) | 491 (71) | 552 (93) |
| RT false alarms (msec) | 556 (144) | 640 (166) | 581 (164) | 648 (175) | 585 (149) | 610 (168) | 548 (131) | 605 (171) | 562 (134) | 631 (161) | 561 (148) | 621 (168) |
| CPT-IP 4-digit | ||||||||||||
| N | 220 | 283 | 199 | 234 | 167 | 184 | 190 | 233 | 210 | 218 | 986 | 1152 |
| d’ | 2.08 (0.85) | 1.22 (0.69) | 2.17 (0.87) | 1.14 (0.70) | 2.06 (0.86) | 1.07 (0.80) | 2.14 (0.89) | 1.24 (0.71) | 2.09 (0.87) | 1.30 (0.80) | 2.11 (0.87) | 1.19 (0.74) |
| Hit rate | 0.76 (0.16) | 0.58 (0.21) | 0.77 (0.17) | 0.55 (0.20) | 0.76 (0.18) | 0.53 (0.24) | 0.78 (0.15) | 0.60 (0.20) | 0.76 (0.16) | 0.59 (0.22) | 0.77 (0.16) | 0.57 (0.22) |
| False alarm rate | 0.13 (0.09) | 0.19 (0.12) | 0.12 (0.09) | 0.19 (0.13) | 0.14 (0.10) | 0.19 (0.13) | 0.13 (0.10) | 0.20 (0.13) | 0.13 (0.09) | 0.18 (0.12) | 0.13 (0.10) | 0.19 (0.12) |
| RT hits (msec) | 536 (73) | 597 (98) | 541 (79) | 605 (98) | 535 (85) | 586 (114) | 532 (69) | 589 (107) | 524 (76) | 573 (92) | 533 (77) | 590 (102) |
| RT false alarms (msec) | 567 (120) | 611 (113) | 565 (119) | 624 (125) | 563 (119) | 594 (134) | 558 (101) | 615 (131) | 545 (106) | 594 (124) | 560 (113) | 609 (125) |
Note: CPT = Continuous Performance Test; DS-CPT = Degraded Stimulus CPT; CPT-IP = CPT, Identical Pairs; RT = response time. Except for Ns, numbers represent M (SD).