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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Behav Brain Res. 2014 Oct 2;278:115–128. doi: 10.1016/j.bbr.2014.09.012

Figure 5. DKO mice exhibit decreased social approach behavior in a three-chamber social behavior assay.

Figure 5

(a) Social index (calculated as: time spent near cage with novel mouse / [time spent near cage with novel mouse + time spent near empty cage] *100) was decreased in DKOs. Thus, a social index <50 indicates a social aversion, while >50 indicates a preference for social affiliation. (b) DKOs spent significantly less time in the social zone and significantly more time in the center (home) zone. (Data expressed as mean ± SEM; **p<0.01, ***p<0.001)