Table 2.
Accuracy and time comparison for manual point counting and QuHAnT.
| Quantitation method |
Grid densitya (W × H) |
Volume density (%) |
Analysis time (image−1) |
Study analysis (hr)b |
|---|---|---|---|---|
| Point counting | 4 × 4 | 6 | 1–2 min | 45 |
| 16 × 16 | 33 | 5–6 min | 225 | |
| QuHAnT | 1,280 × 1,024 | 28 | 1 secb | 1c |
Note. QuHAnT = quantitative histological analysis tool.
a
Image used for comparison across grid sizes is shown in Figure 4 (top).
b
Manual point counting was performed on 3,123 images, and QuHAnT analysis was performed on 2,756 images.
c
Analysis time was determined based on the use of the Intel Xeon E5620 2.4 GHz core processor with TurboBoost within the High Performance Computing Center at Michigan State University.