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. Author manuscript; available in PMC: 2016 Mar 31.
Published in final edited form as: Circulation. 2015 Feb 20;131(13):1202–1213. doi: 10.1161/CIRCULATIONAHA.114.012669

Figure 3.

Figure 3

Adamts7 deficiency also reduces atherosclerotic burden in the Apoe KO hyperlipidemic mouse model on western diet. A) Quantification of area staining positive for oil-red O for both Adamts7+/+;Apoe−/− and Adamts7−/−;Apoe−/− control littermates from both sexes (Males N=9, 16; Females N=10, 13) after being fed western diet for 10 weeks. B) Representative oil-red O stained aortas from male Adamts7+/+;Apoe−/− and Adamts7−/−;Apoe−/− animals. C) Average lesion area across 5 serial sections from the aortic roots of Adamts7+/+;Apoe−/− and Adamts7−/−;Apoe−/− animals. D) Representative H/E stained sections from male KO and dKO animals used in the studies.