Table 1.
Case # | Pathological diagnosis | Age (years) | Gender | Postmortem delay (h) | Clinical diagnosis and complications | CERAD neuritic plaque score | Braak neurofibrillary tangle stage | Analysis |
---|---|---|---|---|---|---|---|---|
1 | Control | 81 | F | 3.0 | Myocardial infarction, congestive heart failure, renal failure | A | II | qPCR |
2 | Control | 78 | M | 2.7 | Coronary artery disease, chronic, obstructive pulmonary disease, congestive heart failure, diabetes mellitus, hip bone fracture, cardiac pacemaker | 0 | II | qPCR |
3 | Control | 82 | F | 2.0 | Lung cancer, myocardiac infarction | A | II | qPCR |
4 | Control | 73 | F | 1.5 | Ovarian cancer | 0 | I | qPCR |
5 | Control | 85 | F | 2.5 | Cardiac and respiratory failure, atrial fibrillation, cerebrovascular, accident (right hemiplegia) | 0 | III | qPCR |
6 | Control | 78 | M | 1.7 | Lung cancer, heart failure | 0 | I | qPCR, ISH |
7 | Control | 85 | M | 3.2 | Congestive heart failure | 0 | II | qPCR, ISH |
8 | Control | 88 | F | 3.0 | Chronic renal failure | 0 | II | qPCR |
9 | Control | 86 | M | 2.5 | Renal failure, attrial fabrillation, coronary artery disease, congestive heart failure | 0 | II | ISH |
10 | AD | 89 | F | 3.0 | AD, osteoarthritis, anxiety, depression, aspiration pneumonia | C | V | qPCR |
11 | AD | 79 | M | 2.0 | AD | C | V | qPCR |
12 | AD | 89 | F | 3.0 | AD bronchopneumonia | C | V | qPCR |
13 | AD | 80 | F | 2.2 | AD, parkinsonism | C | VI | qPCR |
14 | AD | 91 | F | 3.0 | AD | C | V | qPCR |
15 | AD | 87 | M | 3.0 | AD parkinsonism | C | V | qPCR |
16 | AD | 89 | F | 2.5 | AD | C | VI | qPCR |
17 | AD | 61 | F | 2.5 | AD, uterus cancer, bronchitis | C | VI | ISH |
18 | AD | 73 | F | 2.0 | AD, atrial fibrillation, cerebrovascular accident | C | V | ISH |
19 | AD | 81 | M | 3.0 | AD, cardiac and respiratory failure, | C | V | ISH |
AD: Alzheimer's disease, qPCR: quantitative polymerase chain reaction, ISH: in situ hybridization histochemistry.