Moving hazards of death (blue line) in relation to sum of SUVmax (SUM) interpreted as chance of death per person per month; cubic spline smoothed line (red line) is superimposed. There is upward shift of curve for SUM greater than 20.
From Jadvar H, Desai B, Ji L, et al. Baseline 18F-FDG PET/CT parameters as imaging biomarkers of overall survival in castrate-resistant metastatic prostate cancer. J Nucl Med 2013; 54:1195–1201, with permission.