Table 2.

Systematic reviews that reported on 3Rs

Reference	Year	3Rs	Replacement	Reduction	Refinement
26	1994	No	No	Yes	No
70	2003	No	No	Partial	No
81	2005	No	No	Yes	No
82	2005	No	No	Yes	No
103	2007	Partial	No	No	No
114	2002	Partial	No	Yes	No