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Timelines demonstrating the progress of 3 NC3Rs programs. (A) Applying the 3Rs in asthma research. (B) Rodent Big Brother CRACK IT Challenge. (C) Minimizing the use of nonhuman primates (NHP) in the development of monoclonal antibodies (mAb). AA, Actual Analytics; AZ, Astra Zeneca; HLS, Huntingdon Life Sciences.
