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Selected adverse events in patients treated with vemurafenib, by mutational status
| BRAFV600E (n=295) | BRAFV600K (n=33) | |
|---|---|---|
| Total patients with ≥1 adverse event | 294 (100%) | 33 (100%) |
| Arthralgia | 171 (58%) | 13 (39%) |
| Rash | 123 (42%) | 13 (39%) |
| Fatigue | 133 (45%) | 18 (55%) |
| Photosensitivity | 120 (41%) | 12 (36%) |
| Cutaneous squamous-cell carcinoma | 57 (19%) | 8 (24%) |
| Keratoacanthoma | 29 (10%) | 7 (21%) |
| Skin papilloma | 85 (29%) | 9 (27%) |
| Nausea | 117 (40%) | 8 (24%) |
Data are number of patients (%).
