Table 2.
Initiated BUP/NX induction | Completed induction | Completed detoxification | Weekly counseling1 (≥75% sessions weeks 1–12) | Monthly counseling1 (≥75% sessions months 4–12) | |
---|---|---|---|---|---|
Initial induction/detoxification and counseling | |||||
ST-MAT | 626/627 (100%) | 554/627 (88%) | 502/627 (80%) | 361/545 (66%) | 215/366 (59%) |
LT-MAT | 623/623 (100%) | 564/623 (91%) | N/A | 453/541 (84%) | 271/385 (70%) |
Significance | p<.001 | p<.001 | |||
ST-MAT: BUP/NX dosing during follow-up | |||||
26 week induction (optional) | 153/440 (35%) | 137/153 (90%) | 130/153 (85%) | ||
LT-MAT: BUP/NX dosing during follow-up | |||||
Weeks 1–4 | Weeks 13–16 | Weeks 25–28 | Weeks 33–36 | Weeks 45–48 | |
Received ≥75% of doses2 | 519/612 (85%) | 331/552 (60%) | 275/499 (55%) | 245/474 (52%) | 187/432 (43%) |
Received any BUP/NX dose3 | 590/612 (96%) | 416/552 (75%) | 345/499 (69%) | 294/474 (62%) | 239/432 (55%) |
Retained in BUP/NX treatment4 | 597/612 (98%) | 449/552 (81%) | 370/499 (74%) | 317/474 (67%) | 239/432 (55%) |
ST-MATMAT = Short term medication assisted arm, LT-MAT = Long term medication assisted arm,
At the time the study was halted, 1087 had completed the 12 weekly and 751 the 9 monthly counseling sessions
Received at least 75% of thrice weekly dosing throughout the period
Received any BUP/NX dose in the period
Received BUP/NX dose at any point during or after the period