Table 2.

Association between nuclear features and recurrence

Variables	N	%	5-yr RFP (%)	p value
Nuclear diameter				0.007
Small	232	48	86
Intermediate	150	31	82
Large	103	21	74
Nuclear atypia				0.006
Mild	231	48	87
Moderate	139	29	81
Severe	115	24	75
Nuclear/cytoplasmic ratio				0.068
Low/ Intermediate	391	81	80
High	94	19	91
Chromatin pattern				0.092
Homogeneous	85	18	87
Fine granular	229	47	83
Coarse granular	171	35	79
Prominence of nucleoli				0.059
Indistinct	133	27	87
Distinct	217	45	82
Large	135	28	87
Intranuclear inclusion				0.190
Absence	441	91	82
Presence	44	9	88
Mitotic count				<0.001
Low	204	42	91
Intermediate	106	22	80
High	175	36	73
Atypical mitoses				<0.001
Absence	362	75	86
Presence	123	25	72

Abbreviation: RFP, recurrence-free probability

Significant p-values are shown in bold: all p-values from log-rank test.