Table 3.
Results of multivariate Cox proportional hazards model
| Variable | HR | 95% CI | p value |
|---|---|---|---|
| Sex (male vs. female) | 1.98 | 1.26 – 3.09 | 0.003 |
| Stage (IB vs. IA) | 1.58 | 0.96– 2.60 | 0.072 |
| Pleural invasion | 1.31 | 0.77 – 2.23 | 0.325 |
| Lymphatic invasion | 1.21 | 0.72 – 2.03 | 0.475 |
| Vascular invasion | 1.04 | 0.62 – 1.75 | 0.878 |
| Necrosis | 2.34 | 1.41 – 3.90 | 0.001 |
| Architectural/mitotic grade | |||
| intermediate vs. low | 1.94 | 0.99 – 3.81 | 0.053 |
| high vs. low | 2.96 | 1.39 – 6.28 | 0.005 |
Abbreviations: Hazard ratio, HR; confidence interval, CI
Significant p-values are shown in bold.