Table 4.
Multivariate logistic regression of platelet aggregation variables predicting MSIMI (MSIMI/NLVR) status
| Variables | Odds Ratio(95%CI)* | P-value |
|---|---|---|
| Δ Platelet Aggregation | ||
| ADP, 5 μM | 1.005(0.998 – 1.013) | .19 |
| Epinephrine, 10 μM | 1.009(1.000 – 1.017) | .054 |
| Collagen, 10 μM | 1.006(1.000 – 1.012) | .053 |
| Individual Agonist Composite Score | 1.57(1.05 – 2.36) | .028 |
| Serotonin+ ADP | 1.012(1.005–1.02) | .001 |
| Serotonin+Epinephrine | 1.003(0.998 – 1.009) | .25 |
| Serotonin+Collagen | 1.003(0.998 – 1.009) | .22 |
| Serotonin + Agonist Composite Score | 1.59(1.07 – 2.37) | .022 |
| Resting Platelet Aggregation | ||
| ADP, 5 μM | 1.000(0.997 – 1.004) | .80 |
| Epinephrine, 10 μM | 1.000(0.996 – 1.004) | .94 |
| Collagen, 10 μM | 1.002(0.998 – 1.006) | .36 |
| Serotonin+ ADP | 1.000(0.997 – 1.004) | .93 |
| Serotonin+Epinephrine | 0.999(0.995 – 1.003) | .77 |
| Serotonin+Collagen | 1.002(0.998 – 1.006) | .37 |
Odds ratios reflect the change in the odds of having MSIMI associated with an increase of one unit in the platelet aggregation variables.
Models included age, sex, smoking status, BDI-scores and resting LVEF.