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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: J Orthop Res. 2014 Nov 18;33(3):334–342. doi: 10.1002/jor.22761

Figure 4.

Figure 4

Micro-CT quantification of morphologic bone changes, expressed as change relative to non-irradiated control limbs (experimental - average value of 0 Gy limbs) +/− SEM (n=2–6 per time point). Over the distal 5mm of the femur, bone volume (A) was increased following irradiation, and bone mineral density (B) also increased following a brief, transient decrease at 1 week in the 5 Gy group. Radiation-induced cortical thickening was demonstrated by an increase in the BV (C) over a 1mm thick distal femur volume of interest. Loss of trabecular bone (D) was most pronounced in the 4x5 Gy group.