Table 1.
Patients’ characteristics
| Total (n = 77) | Pranlukast (n = 37) | Placebo (n = 40) | P value | |
|---|---|---|---|---|
| Age (y), mean (SD) | 1.9 ± 0.6 | 1.8 ± 0.5 | 1.9 ± 0.6 | 0.71*1 |
| Males, no. (%) | 56 (73) | 29 (78) | 27 (68) | 0.28*2 |
| Comorbidity*3 | ||||
| Food allergy, no. (%) | 39 (51) | 20 (54) | 19 (48) | 0.57*2 |
| Atopic dermatitis, no. (%) | 32 (42) | 14 (38) | 18 (45) | 0.52*1 |
| Total IgE (IU), median (25% – 75%) | 214 (76 – 585) | 224 (64 – 536) | 204 (106 – 771) | 0.77*4 |
| Allergen-specific IgE (IU), median (25% – 75%) | ||||
| Mite | 5.8 (0.4 – 49) | 5.6 (0.4 – 48) | 6.1 (0.3 – 49) | 0.42*4 |
| Egg | 5.6 (1.1 – 26) | 12 (0.9 – 29) | 3.2 (1.3 – 15) | 0.26*4 |
| Milk | 0.7 (0. 4 – 4.3) | 1.3 (0.4 – 9.9) | 0.7 (0.4 – 2.5) | 0.34*4 |
| Wheat | 0.6 (0.3 – 3.1) | 0.5 (0.3 – 3.5) | 0.7 (0.3 – 2.2) | 0.96*4 |
| Eosinophils (%), median (25% – 75%) | 3.6 (1.4 – 5.0) | 4.0 (1.4 – 5.0) | 3.3 (1.0 – 5.0) | 0.71*4 |
*1P value was calculated by Student’s t-test. *2P value was calculated by the χ2 test. *3Comorbidity was diagnosed by collaborating pediatricians. *4P value was calculated by the Mann–Whitney test.