Table 2.
Burden analysis of CNV Regions reveals a higher number of CNVs in genes in individuals with narrow bipolar phenotype (BPI and BPII)
| Unaffected | Broad | Narrow | |
|---|---|---|---|
| No. All CNVs | 28.1 | 28.7 | 29.5 |
| P vs unaffected | - | 0.39 | 0.26 |
| No. All CNVs in genes | 15.6 | 16.8 | 17.3 |
| P vs unaffected | - | 0.16 | 0.11 |
| No. Rare CNVs in genes | 9.7 | 11.0 | 11.3 |
| P vs unaffected | - | 0.12 | 0.09 |
| No. CNVs in disease genes | 4.8 | 5.5 | 5.7 |
| P vs unaffected | - | 0.11 | 0.06 |
| No. Rare CNVs in disease genes | 4.0 | 4.8 | 5.0 |
| P vs unaffected | - | 0.07 | 0.06 |
A trend towards an increased number of CNVs in disease genes in individuals with narrow bipolar phenotype is also reported.