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. 2015 Mar 20;6:6340. doi: 10.1038/ncomms7340

Figure 8. Intracranial injection of LV-TIM3-GFP into the brain of LysM-Hif-1α−/− mice increases infarct size and neurological deficit.

Figure 8

(a) Representative fluorescence images (excitation filter, from 445 to 490 nm, and emission filter, from 515 to 575 nm) of mice injected with PBS, LV-GFP or LV-TIM3-GFP using IVIS Spectrum system (Xenogen IVIS-200). (b) Representative images of TTC-stained brain slices from mice expressing LV-TIM3-GFP or LV-GFP. (c,d) Infarct size (c, n=6 for LV-GFP or n=5 for LV-TIM3-GFP) and neurological score (d, n=6 for each group) were examined 24 h after H/I. The data were analysed by Mann–Whitney U-test; P=0.046.