Table I.

Correlation coefficient (r), p-value and IC₅₀ value of individual cranberry PACs and flavonols against SKOV-3 and OVCAR-8 cells.^a

	SKOV-3			OVCAR-8
Compound	Correlation coefficient	p-value	IC50 (μg/ml)	Correlation coefficient	p-value	IC50 (μg/ml)
DP-2	−0.917	0.0000263	194.8	−0.919	0.0000239	143.1
DP-3	−0.804	0.00163	210.8	−0.513	0.0882	ND
DP-4	−0.923	0.0000185	200.0	−0.936	0.00000741	164.1
DP-5	−0.983	1.15×10−8	126.3	−0.738	0.00616	209.9
DP-6	−0.929	0.0000129	201.1	−0.9	0.0000674	152.6
DP-7	−0.821	0.00106	288.7	−0.736	0.00631	211.2
DP-8	−0.944	0.00000397	137.9	−0.945	0.00000356	125.7
DP-9	−0.939	0.00000584	81.9	−0.923	0.0000189	137.8
DP-10	−0.494	0.103	ND	−0.565	0.0558	ND
DP-11	−0.966	3.53×10−7	165.9	−0.931	0.0000107	146.9
DP-12	−0.824	0.000978	162.6	−0.791	0.00216	248.5
M-Gal	0.331	0.293	ND	−0.78	0.00275	130.7
Q-Gal	−0.833	0.000757	164.8	−0.896	0.000082	132.7
Q-Glu	−0.899	0.0000684	160.6	−0.929	0.000013	160.6
Q-A-P	−0.665	0.0182	410.2	−0.777	0.00293	212.7
Q-A-F	−0.791	0.00217	173.5	−0.908	0.0000435	171.2
Q-Xylo	0.095	0.77	ND	−0.266	0.404	ND
Q-Rhamno	−0.879	0.000167	207.4	−0.945	0.00000369	163.4
Q-Aglycone	−0.982	1.45×10−8	83.2	−0.966	3.48×10−7	61.1

^aLinear regression was conducted for each cranberry flavonoid between cell viability and compound concentration (untransformed and logarithm-transformed). IC₅₀ value was calculated based on best-fit regression model (r closer to −1).

ND, not determined; M-Gal, myricetin-3-galactoside; Q-Gal, quercetin-3-galactoside; Q-Glu, quercetin-3-glucoside; Q-A-P, quercetin-3-arabinopyranoside; Q-A-F, quercetin-3-arabinofuranoside; Q-Xylo, quercetin-3-xylopyranoside; Q-Rhamno, quercetin-3-rhamnopyranoside; Q-Aglycone, quercetin aglycone.