Table 2.
Genotype frequencies by fibrosis grade in patients with chronic hepatitis C
| F1 and F2 | F3 and F4 | OR (95% CI) | P value | |
|---|---|---|---|---|
| NOX4 (rs3017887) | N = 105 | N = 73 | 0.60 (0.22 to 1.59) | 0.31 |
| CC | 0.532 | 0.588 | ||
| CA | 0.457 | 0.372 | ||
| AA | 0.011 | 0.040 | ||
| MAF | 0.239 | 0.226 | ||
| CYBA (675 T → A) | 0.29 (0.06 to 1.11) | 0.09 | ||
| TT | 0.800 | 0.882 | ||
| TA | 0.190 | 0.118 | ||
| AA | 0.010 | 0.000 | ||
| MAF | 0.105 | 0.059 |
Genotype frequencies of NOX4 rs3017887 and of CYBA −675 T → A (unregistered) single nucleotide polymorphisms by fibrosis grade in patients with chronic hepatitis C. Odds ratio (OR) and 95% confidence interval (95% CI) for the minor allele of the genotyped SNPs in a dominant model of logistic regression analysis adjusted for age, gender, metabolic syndrome status, triglycerides, plasmatic albumin concentrations, and HCV genotype. MAF, minor allele frequency (frequency of the rarer allele, A for both SNPs).