Table 2.
Dependent variable: probability of developing AD in the next 10 years (0–100)
| ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
(A) Overall sample N = 725 |
(B) Age 64 or under N = 300 |
(C) Age 65 or older N = 425 |
(D) Including “self-rated memory decline” N = 725 |
(E) Including “self-rated longevity expectation” N = 679 |
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Coefficient (SE) | P-value | Coefficient (SE) | P-value | Coefficient (SE) | P-value | Coefficient (SE) | P-value | Coefficient (SE) | P-value | |
Self-rated memory decline | 11.16‡ (2.63) | <0.001 | ||||||||
Longevity expectation (0–100) | −0.10‡ (0.04) | 0.006 | ||||||||
Known risk factors of AD | ||||||||||
Age | −0.02 (0.12) | 0.85 | 0.57* (0.32) | 0.081 | −0.64‡ (0.21) | 0.0031 | −0.01 (0.12) | 0.93 | 0.04 (0.13) | 0.75 |
Cognitive functioning (0–27) | −0.75‡ (0.28) | 0.0063 | −0.58 (0.42) | 0.17 | −0.96† (0.38) | 0.012 | −0.70† (0.27) | 0.010 | −0.70† (0.29) | 0.014 |
Physical activity | −4.57† (2.03) | 0.025 | −4.21 (3.02) | 0.16 | −5.57* (2.86) | 0.053 | −3.99† (2.02) | 0.048 | −4.07† (2.06) | 0.049 |
Cardiovascular disease | ||||||||||
Stroke | 4.09 (4.81) | 0.40 | −2.32 (8.49) | 0.79 | 9.01 (6.06) | 0.14 | 3.33 (4.84) | 0.49 | 3.37 (5.05) | 0.51 |
Heart attack | −8.02 (6.95) | 0.25 | −11.44 (10.30) | 0.27 | −4.71 (9.54) | 0.62 | −8.28 (7.12) | 0.25 | −8.88 (8.17) | 0.28 |
Diabetes | 3.19 (2.74) | 0.25 | 1.73 (3.72) | 0.65 | 3.60 (3.76) | 0.34 | 2.88 (2.70) | 0.29 | 2.90 (2.84) | 0.31 |
Any ADL limitation | 0.57 (3.31) | 0.86 | 6.77 (5.10) | 0.19 | −1.73 (4.35) | 0.69 | −1.46 (3.25) | 0.65 | 1.78 (3.62) | 0.62 |
Other sociodemographic factors | ||||||||||
Female | 2.26 (2.16) | 0.30 | 4.65 (3.05) | 0.11 | −0.51 (2.99) | 0.85 | 2.54 (2.12) | 0.21 | 2.09 (2.19) | 0.32 |
Race/ethnicity (ref: non-Latino white) | ||||||||||
Black | −8.35* (4.31) | 0.053 | 1.92 (6.54) | 0.77 | −16.86‡ (5.59) | 0.0027 | −7.93* (4.31) | 0.066 | −6.71 (4.75) | 0.16 |
Latino | −6.71 (4.32) | 0.12 | −6.42 (5.01) | 0.20 | −7.58 (7.47) | 0.31 | −6.37 (4.14) | 0.12 | −7.91* (4.48) | 0.078 |
Other race | 8.64 (8.96) | 0.34 | −1.99 (11.44) | 0.86 | 9.30 (11.74) | 0.43 | 7.39 (9.60) | 0.44 | 8.54 (8.69) | 0.33 |
Education (ref: high school graduate) | ||||||||||
Less than high school | 1.44 (3.01) | 0.63 | −2.72 (4.97) | 0.59 | 4.14 (3.82) | 0.28 | 1.78 (2.96) | 0.55 | 1.44 (3.16) | 0.65 |
Some college | −1.36 (2.20) | 0.54 | −4.97 (3.18) | 0.12 | 1.57 (3.08) | 0.61 | −1.38 (2.17) | 0.53 | −0.67 (2.29) | 0.77 |
Married | 1.18 (2.55) | 0.64 | 4.56 (3.96) | −2.02 (3.41) | 0.55 | 1.22 (2.49) | 0.63 | −0.19 (2.64) | 0.94 | |
Constant | 43.56‡ (11.25) | <0.001 | −1.03 (21.60) | 0.96 | 95.96‡ (19.84) | <0.001 | 39.48‡ (11.07) | <0.001 | 43.97‡ (11.76) | <0.001 |
R-squared | 0.04 | 0.07 | 0.06 | 0.07 | 0.06 |
P < 0.1,
P < 0.05,
P < 0.01.
AD, Alzheimer’s disease; ADL, activity of daily living; SE, standard error.