Table 3.

Common content domains from disease-specific, patient-reported measures of treatment burden mapped onto the final conceptual framework themes

Common content domains (12)	Framework theme (3)
– Treatment convenience	Theme 1: work patients must do to care for health
– Self-care convenience
– Monitoring burden
– Diet/food-related issues
– Medical device bother
– Medication side-effects	Theme 2: challenges/stressors that exacerbate burden
– Family conflict
– Economic burden
– Scheduling flexibility
– Lifestyle impact (role and social)	Theme 3: impacts of burden
– Emotional/regimen distress
– Overall treatment burden