Table 1. Baseline demographics.
Baseline demographics by type of chemotherapy or patients receiving fosaprepitant | ||||
---|---|---|---|---|
| ||||
AC (N=99) | Platinum (N=81) | Total (N= 180) | p value | |
Age at time of chemo | 0.0266a | |||
N | 99 | 81 | 180 | |
Mean (SD) | 53.3 (9.7) | 56.4 (13.2) | 54.7 (11.5) | |
Median | 55.0 | 57.0 | 56.0 | |
Range | (31.0–74.0) | (22.0–77.0) | (22.0–77.0) | |
Gender | <0.0001b | |||
Male | 2 (2.0 %) | 50 (61.7%) | 52 (28.9 %) | |
Female | 97 (98.0 %) | 31 (38.3 %) | 128 (71.1 %) | |
Ethnicity | 0.2069b | |||
White | 91 (91.9%) | 77 (95.1 %) | 168 (93.3 %) | |
Black | 2 (2.0 %) | 0 (0.0 %) | 2 (1.1 %) | |
Asian | 0 (0.0 %) | 1 (1.2 %) | 1 (0.6 %) | |
Hispanic | 3 (3.0 %) | 1 (1.2 %) | 4 (2.2 %) | |
Other | 3 (3.0 %) | 0 (0.0 %) | 3 (1.7%) | |
American Indian | 0 (0.0 %) | 1 (1.2 %) | 1 (0.6 %) | |
Middle Eastern | 0 (0.0 %) | 1 (1.2 %) | 1 (0.6 %) | |
Primary cancer diagnosis | <0.0001b | |||
Breast | 98 (99.0 %) | 4 (4.9 %) | 102 (56.7 %) | |
Lung | 0 (0.0 %) | 20 (24.7 %) | 20 (11.1 %) | |
GI | 0 (0.0 %) | 12 (14.8%) | 12 (6.7%) | |
Reproductive or genitourinary | 1 (1.0 %) | 15 (18.5 %) | 16 (8.9%) | |
Other | 0 (0.0 %) | 7 (8.6 %) | 7 (3.9 %) | |
Endo | 0 (0.0 %) | 6 (7.4 %) | 6 (3.3 %) | |
Head | 0 (0.0 %) | 17 (21.0%) | 17 (9.4%) | |
Prior history of chemo | <0.0001b | |||
No | 84 (84.8 %) | 40 (49.4 %) | 124 (68.9 %) | |
Yes | 15 (15.2%) | 41 (50.6 %) | 56 (31.1 %) | |
Metastasis | <0.0001b | |||
Yes | 2 (2.0 %) | 22 (27.2 %) | 24 (13.3 %) | |
No | 97 (98.0 %) | 59 (72.8 %) | 156 (86.7%) | |
Corticosteroid use | 0.3644b | |||
No | 1 (1.0 %) | 0 (0.0 %) | 1 (0.6 %) | |
Yes | 98 (99.0 %) | 81 (100.0 %) | 179 (99.4 %) | |
Prior use of fosaprepitant | –b | |||
No | 99 (100.0 %) | 81 (100.0 %) | 180 (100.0%) | |
Prior use of aprepitant | <0.0001b | |||
No | 98 (99.0 %) | 57 (70.4 %) | 155 (86.1 %) | |
Yes | 1 (1.0 %) | 24 (29.6 %) | 25 (13.9 %) |
AC anthracycline-cyclophosphamide
Kruskal Wallis
Chi-Square