Figure 3.
The response to insulin peptide in hybridomas generated from insulin B:9-23 peptide immunized12-4.1 TCR α+Cα−/− mice (Figure 3A) and BDC12-4.4 TCR α+Cα−/− retrogenic mice spleen cells or pancreatic lymph node cells (Figure 3B). Blank bar: stimulation index of tetanus toxin peptide. Black bar: stimulation index of insulin B19A or B:9-23 peptide. Names of hybridoma reflect source of cells (L: cells are from pancreatic lymph node lymphocytes. SP: cells are from splenocytes.)