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. Author manuscript; available in PMC: 2015 Apr 2.
Published in final edited form as: Gastrointest Cancer. 2015 Feb 1;5:61–71. doi: 10.2147/GICTT.S72274

Figure 5.

Figure 5

HIF-1α is variably expressed in a UNC cohort of human CC and may influence disease severity.

Notes: (A and B) human CC tumors were stained for HIF-1α expression, demonstrating an example of high expression (A) and low expression (B). Human tumors were also stained for phosphor-S6, with all tumors displaying positive expression of this marker, example shown in (C). (D) Kaplan–Meier curve demonstrates survival data from a cohort of 27 human CC patients based on HIF-1α expression.

Abbreviations: UNC, University of North Carolina; CC, cholangiocarcinoma.