Table 4.

Multivariable analysis comparing the ND^* and 22q11.2DS^† groups for incidence rate of cardiac and non-cardiac surgeries, hospitalizations, and cardiac catheterizations

Dependent variables		Beta	SE	OR‡	95% CI	P value
Cardiac Catheterizations		0.32	0.19	1.38	0.95; 2.01	0.09
Non-Cardiac Surgeries		1.26	0.24	3.54	2.23; 5.62	<0.0001
Hospitalizations		0.60	0.14	1.82	1.39; 2.38	<0.0001
Total cardiac surgeries§		0.18	0.10	1.20	0.99; 1.45	0.07
Primary cardiac surgeries adjusting for time from birth to last primary surgery and PV anatomy∥
Genotype	22q11.2DS vs. ND	0.19	0.18	1.21	0.85; 1.72	0.29
PV∥ Anatomy§	PA# vs. PS**	−0.28	0.17	0.76	0.55; 1.06	0.10
	Abs. PV†† vs. PS**	2.06	0.35	7.83	3.98; 15.39	<0.0001
Subsequent surgeries adjusting for time from last primary surgery to last follow up and PV anatomy
Genotype	22q11.2DS vs. ND	0.49	0.35	1.63	0.83; 3.22	0.16
PV Anatomy	PA vs. PS	0.33	0.39	1.40	0.65; 2.9	0.39
	Abs. PV vs. PS	1.14	0.43	3.13	1.34; 7.30	0.008

^*ND = non-deleted

^†22q11.2DS = 22q11.2 deletion syndrome

^‡Odds ratios correspond to the independent association of genotype 22q11.2DS with outcome after adjusting for age and years of follow up.

^§Adjusting for presenting pulmonary valve anatomy

^∥PV = pulmonary valve

^#¶PA = pulmonary atresia

^**#PS = pulmonary stenosis

^††**Abs PV= absent pulmonary valve leaflets