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. Author manuscript; available in PMC: 2015 Apr 2.
Published in final edited form as: Cancer Res. 2006 Oct 1;66(19):9379–9384. doi: 10.1158/0008-5472.CAN-06-2646

Figure 2.

Figure 2

RNAi-mediated disruption of PKCε inhibits invasion and motility in UMSCC11A and UMSCC36. A, siRNA-PKCε UMSCC11A and UMSCC36 clones have reduced PKCε protein levels. B, PKCε-deficient UMSCC11A and UMSCC36 clones are significantly less invasive than siRNA-scrambled control cells or untransfected parental cells. *, P < 0.006 for siRNA-PKCε UMSCC11A and P < 0.01 for siRNA-PKCε UMSCC36 compared with siRNA-scrambled control cells. C, PKCε-deficient UMSCC11A and UMSCC36 clones are significantly less motile than siRNA-scrambled control cells or untransfected parental cells. *, P < 0.0005 for siRNA-PKCε UMSCC11A and P < 0.0001 for siRNA-PKCε UMSCC36 compared with siRNA-scrambled control cells. D, representative cell motility field for each cell line and PKCε-deficient clone.

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