Table 2.
Renal findings at renal biopsy by LN class.
| Total (N = 244) |
Class II (N = 7) |
Class III (N = 38) |
Class IVG (N = 117) |
Class IVS (N = 39) |
Class V (N = 43) |
|
|---|---|---|---|---|---|---|
| Levels of clinical and laboratory findings | ||||||
| SBP (mmHg) | 138.9 ± 22.7 | 118.4 ± 14.7 | 131.1 ± 17.9 | 144.2 ± 22.8* | 139.3 ± 22.3* | 134.6 ± 23.9 |
| DBP (mmHg) | 85.8 ± 14.4 | 76.1 ± 10.7 | 81 ± 12.1 | 89.5 ± 14.2†∗ | 86.1 ± 14.8 | 81.1 ± 13.9 |
| Hemoglobin (g/dL) | 10.7 ± 2.2 | 12.5 ± 1.3 | 11.2 ± 2.2 | 10 ± 2.2†∗ | 10.7 ± 1.5† | 12 ± 1.9 |
| BUN (mg/dL) | 27.9 ± 21.4 | 14.7 ± 4.7 | 18.4 ± 12.3 | 33.5 ± 24.3†∗ | 28.8 ± 17.4 | 22.2 ± 19.6 |
| Serum creatinine (mg/dL) | 1.3 ± 1 | 1.2 ± 0.8 | 0.9 ± 0.5 | 1.5 ± 1.1† | 1.3 ± 1 | 1.1 ± 1.1 |
| Estimated GFR (mL/min/1.73 m2) | 80.2 ± 38.3 | 76 ± 32.4 | 98.2 ± 31.7 | 68.4 ± 37.2† | 82 ± 36.9 | 95.3 ± 38.2 |
| Serum cholesterol (mg/dL) | 287.2 ± 107.6 | 225.7 ± 45.7 | 249.5 ± 74.5 | 296.2 ± 105.6 | 302 ± 138.3 | 297.3 ± 113.9 |
| Serum albumin (g/dL) | 2.9 ± 0.7 | 3.9 ± 0.5 | 3 ± 0.8* | 2.8 ± 0.6* | 2.9 ± 0.6* | 2.9 ± 0.6* |
| UPCR (g/g creatinine) | 4.4 ± 3.2 | 1.3 ± 0.5† | 3.4 ± 2.4* | 4.7 ± 3.3* | 4.2 ± 2.4* | 5.1 ± 3.8* |
| Percentages of clinical and laboratory findings | ||||||
| Hypertension (n, %) | 163 (66.8%) | 3 (42.9%) | 18 (47.4%) | 92 (78.6%)† | 26 (66.7%) | 24 (55.8%) |
| Microscopic hematuria (n, %) | 157 (64.3%) | 4 (57.1%) | 24 (63.2%)† | 86 (73.5%)† | 29 (74.4%)† | 14 (32.6%) |
| GFR < 50 mL/min/1.73 m2 | 68 (27.9%) | 2 (28.6%) | 5 (13.2%) | 44 (37.6%)† | 10 (25.6%) | 7 (16.3%) |
| Nephrotic range proteinuria (n, %) | 125 (51.2%) | — | 14 (36.8%) | 67 (57.3%)* | 19 (48.7%)* | 25 (58.1%)* |
| Nephrotic syndrome (n, %) | 74 (30.3%) | — | 7 (18.4%) | 39 (33.3%)* | 10 (25.6%) | 18 (41.9%)* |
| Anti-dsDNA (n, %) | 190 (77.9%) | 3 (42.9%) | 33 (86.8%)* | 92 (80.7%)* | 32 (86.5%)* | 30 (69.8%) |
Data are mean ± SD, median with interquartile range and percentages; † P < 0.05 versus class V and * P < 0.05 versus class II. BUN: blood urea nitrogen, DBP: diastolic blood pressure, and GFR: glomerular filtration rate. UPCR: urine protein creatinine ratio and SBP: systolic blood pressure.