Table 1.
Expression of NRP-1 protein in 74 cervical tissues.
| Factor | Classification | n | NRP-1 positive (%) | P * |
|---|---|---|---|---|
| Age | >40 y | 33 | 23 (69.70) | >0.05 |
| ⩽40 y | 7 | 6 (85.71) | ||
|
| ||||
| Clinical stage | Controls* | 20 | 4 (20.0) | <0.01 |
| CIN | 14 | 10 (71.43) | ||
| LECC | 25 | 18 (72.0) | ||
| LACC | 15 | 11 (73.33) | ||
|
| ||||
| Nodal metastasis** | Absent | 28 | 21 (75.0) | >0.05 |
| Present | 12 | 8 (66.67) | ||
|
| ||||
| Pathological grade | HG1 | 7 | 5 (71.43) | 0.037 |
| HG2 | 25 | 21 (84.0) | ||
| HG3 | 8 | 3 (37.5) | ||
|
| ||||
| Pathological types | SCC | 31 | 22 (70.97) | >0.05 |
| ACC | 9 | 7 (77.77) | ||
SCC: squamous cancer, ACC: adenocarcinoma, CIN: cervical intraepithelial neoplasia, LECC: local early cervical cancer, stage I a1 to I b1, and LACC: local advanced cervical cancer, stage I b2 to IIa. *The occurrence of NRP-1 protein of this group was much lower than that of the other 3 groups. **Pelvic lymphatic nodes involved only.