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Vital sign data for the 3 cohorts at screening and throughout the infusion. (a) Body temperature, (b) respiration, (c) pulsation, (d) diastolic pressure, and (e) systolic pressure at the 3 different doses: 56 mg/m2 (n = 3), 74 mg/m2 (n = 14), and 98 mg/m2 (n = 4).
