Table 1.
Characteristics of Included Clinical Trials
| Clinical Trial | Participating Countries | Publication Year | Mean follow-up (mos) | Eligible LVEF | Factorial Comparison | Total Subjects Enrolled | Subjects included in this study |
|---|---|---|---|---|---|---|---|
| MADIT-I | USA, Italy, Germany |
1996 | 26.8 | ≤ 35% | ICD v. usual medical therapy |
196 | 176 |
| MADIT-II | USA, Netherlands Germany, Israel |
2002 | 20.2 | ≤ 30% | ICD v. usual medical therapy |
1232 | 1080 |
| SCD-HeFT | USA, Canada | 2005 | 40.2 | ≤ 35% | ICD v. placebo v. amiodarone |
2521 | 1611 |
Abbreviations: LVEF, left ventricular ejection fraction; ICD, implantable cardioverter defibrillator.