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Effects of TZDs on apoptosis, migration, invasion, and proliferation of cancer cells and on inflammation. In some ellipses, only one representative is listed; Bax and p53 react similarly, as well as p27 and p21. MMPs represents MMP-2 and MMP-9 and Cyclin E represents cyclin D1, cyclin B1, CDK2, and CDK4. Abbreviations: EGF: epithelial growth factor receptor; PPRE: PPARγ response element, Surv: survivin, E-cad: E-cadherin, b-cat: β-catenin, Cytok: cytokines.
