Table 1.
Baseline characteristics of patients with PCOS. Comparison of baseline characteristics of PCOS patients with (PCOS-IR) and without IR (PCOS-C). Data were analyzed by t-tests, Mann-Whitney U test (for BARD-Scores), or Chi²-tests (for dichotomous variables). Values are given as mean ± standard deviation, unless otherwise indicated.
| Parameter | PCOS-C (n = 36) |
PCOS-IR (n = 53) |
P |
|---|---|---|---|
| HOMA-IR [mmol∗mU/L²] | 1.4 ± 0.7 | 4.9 ± 2.6 | 0.0001 |
| Fasting insulin [µU/mL] | 6.3 ± 3.1 | 20.8 ± 9.9 | 0.0001 |
| AUCI [mU∗h/L] | 127 ± 48 | 300 ± 141 | 0.0001 |
| Testosterone [nmol/L] | 2.5 ± 0.9 | 2.7 ± 0.8 | NS |
| FAI | 4.7 ± 3.3 | 13.2 ± 16.6 | 0.001 |
| BMI [kg/m²] | 26.8 ± 6.4 | 35.8 ± 8.5 | 0.0001 |
| Body weight [kg] | 75.9 ± 21.1 | 101.0 ± 25.0 | 0.0001 |
| Cholesterol [mg/dL] | 186 ± 28 | 188 ± 33 | NS |
| LDL-cholesterol [mg/dL] | 102 ± 22 | 112 ± 30 | NS |
| HDL-cholesterol [mg/dL] | 63 ± 14 | 48 ± 10 | 0.0001 |
| Triglycerides [mg/dL] | 84 ± 48 | 161 ± 166 | 0.002 |
| MBS [%] | 5.6 | 69.8 | 0.0001 |
| AST [U/L] | 25 ± 29 | 21 ± 6 | NS |
| ALT [U/L] | 26 ± 14 | 30 ± 12 | NS |
| AST/ALT-ratio | 0.89 ± 0.3 | 0.72 ± 0.2 | 0.002 |
| LIFL [%] | 22.2 | 35.8 | NS |
| BARD-Score [median (25th, 75th percentile)] | 2 (0.25, 2.75) | 1 (1, 3) | NS |
| M30 [U/L] | 198 ± 91 | 220 ± 170 | NS |
| NASH [%] | 5.6 | 5.7 | NS |