Table 4.
Achievement of clinical targets for HbA1c, blood pressure, and LDL-cholesterol at baseline in BARI 2D by sex.
| Clinical target | % at clinical target | Odds ratio (95% CI)† | |||
|---|---|---|---|---|---|
| Female (N = 686) |
Male (N = 1635) |
P value | Unadjusted female versus male | Adjusted† female versus male | |
| HbA1c < 7% | 31.9% | 42.3% | <0.001 | 0.64 (0.53, 0.77) | 0.71 (0.57, 0.88) |
| Blood pressure ≤ 130/80 mm Hg | 45.0% | 48.6% | 0.12 | 0.87 (0.72, 1.04) | 1.11 (0.92, 1.35) |
| LDL < 100 mg/dL | 49.8% | 63.1% | <0.001 | 0.58 (0.48, 0.69) | 0.64 (0.53, 0.78) |
| Achieved all 3 target goals | 10.9% | 15.8% | 0.002 | 0.65 (0.49, 0.86) | 0.78 (0.58, 1.04) |
†All clinical targets were adjusted for the following common covariates: sex, age, race ethnicity, education, physical activity, cigarette smoking, duration of diabetes, and BMI. In addition, HbA1c was adjusted for a number of diabetes agents; lipids targets were adjusted for a number of lipids agents and CABG or PCI prior to randomization; blood pressure target was adjusted for a number of antihypertensive agents, CABG or PCI prior to randomization, and history of hypertension. The attainment on all 3 targets was controlled for a number of total drugs, CABG or PCI prior to randomization, and history of hypertension.