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. 2015 Apr 2;11(4):e1005061. doi: 10.1371/journal.pgen.1005061

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© 2015 Reschen et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — (A) Normalized FAIRE-seq signal in 2000bp windows centered on the TSS for gene sets grouped by their expression characteristics. OxLDL-induced changes in open chromatin were associated with concordant changes in gene expression (higher FAIRE signal indicates more open chromatin, *** p < 0.0005). (B) Profile view of FAIRE-seq signal around TSSs showing sharply delineated promoter open chromatin profiles and their relationship with expression.