Table 1. Top 10 most up-regulated and down-regulated genes during oxLDL-induced foam cell formation.

	Up-regulated genes			Down-regulated genes
Rank	Gene symbol	Gene	Fold change (log2)	Gene symbol	Gene	Fold change (log2)
1	PLIN2	Perilipin 2	2.70	LDLR	Low Density Lipoprotein Receptor	-3.09
2	AKR1C4	Aldo-Keto Reductase Family 1, Member C4	2.50	F13A1	Coagulation Factor XIII, A1 Polypeptide	-2.81
3	AKR1C3	Aldo-Keto Reductase Family 1, Member C3	2.45	SC4MOL(MSMO1)	Methylsterol Monooxygenase 1	-2.57
4	ABCG1	ATP-Binding Cassette, Sub-Family G (WHITE), Member 1	2.44	SQLE	Squalene Epoxidase	-2.46
5	PDK4	Pyruvate Dehydrogenase Kinase, Isozyme 4	1.95	INSIG1	Insulin Induced Gene 1	-2.15
6	PPAP2B	Phosphatidic Acid Phosphatase Type 2B	1.65	FCGBP	Fc Fragment Of IgG Binding Protein	-2.01
7	LOC644496	Pseudo gene similar to cathepsin L1 preproprotein	1.54	CD93	CD93 Molecule	-2.00
8	TMEM158	Transmembrane Protein 158	1.51	ALOX5AP	Arachidonate 5-Lipoxygenase-Activating Protein	-1.91
9	FABP4	Fatty Acid Binding Protein 4, Adipocyte	1.50	DHCR7	7-Dehydrocholesterol Reductase	-1.83
10	SLC7A11	Solute Carrier Family 7	1.45	FADS1	Fatty acid desaturase 1	-1.81