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. 2015 Apr 2;10(4):e0119642. doi: 10.1371/journal.pone.0119642

Fig 3. Three dimensional (3D) reconstruction of Tβ4 cellular trafficking in HepG2 cells growing at different cell conditions.

Fig 3

3D reconstruction of the main steps of the hypothetical Tβ4 nuclear trafficking from nucleoplasm to nucleolus in HepG2 cells growing in complete medium(1A-4A). In HepG2 cells growing for 48h in the absence of fetal bovine serum, the starvation induced stress could affect the molecular mechanisms involved in the Tβ4 cellular trafficking, preventing the localization of Tβ4 in the nucleolus (1B-4B).