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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Clin Cancer Res. 2015 Jan 29;21(7):1741–1751. doi: 10.1158/1078-0432.CCR-14-1959

Figure 3. Stable overexpression of EcSOD attenuates the malignant phenotype of human pancreatic cancer cell lines.

Figure 3

(A) Stably overexpressing BxPC3 cells and (B) MiaPaCa2 cells were plated to assess colony formation after 2 weeks. Plating efficiency for both Bx-EcSOD and Mia-EcSOD cells decreased compared to control cells. Data represent the relative mean ± SE. p = 0.015 for BxPC3 and 0.044 for MiaPaCa-2.

(C) Growth of overexpressing cells (Bx-EcSOD and Bx-Control) was examined for a total of 96 h. Doubling time in the Bx-EcSOD cells after overexpression increased compared to control cells. Data represent the mean ± SE of cell population doubling time in hours. p = 0.031.