A. Bcl-2 was immunoprecipitated from RS4;11 cells, and subjected to
immunoblotting for Bcl-2 and the indicated pro-apoptotic Bcl-2 family members.
WCE, whole cell extract; Sup, supernatant; IP, immunoprecipitate; eluant,
detergent eluant of immunoprecipitate. Samples were obtained from
immunoprecipitations performed in the absence (−) or presence (+) of
Bcl-2 antibody. Asterisks indicate non-specific bands. B. Bim was
immunoprecipitated from RS4;11 cells, and subjected to immunoblotting for Bim
and Bcl-2. C. Bik was immunoprecipitated from RS4;11 cells, and
subjected to immunoblotting for Bik and Bcl-2.