Fig. 3.

PDZK1 protein expression in the distal ileum of Tnf ^ΔARE+/+ and ^+/− mice. PDZK1 protein expression was analyzed by Western analysis in the total tissue lysates (n = 2 pairs of mice) and scraped mucosa (n = 5 pairs of mice) of distal ileum from Tnf ^ΔARE mice. PDZK1 protein abundance was found to be strongly decreased in both scraped mucosa and total tissue lysates from the distal ileum of Tnf ^ΔARE+/− mice as compared to WT littermates