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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Biomech Model Mechanobiol. 2014 Oct 2;14(3):589–602. doi: 10.1007/s10237-014-0624-2

Figure 4. NRVM Grow at a Similar Rate over Time on Micropost and Flat Substrata.

Figure 4

(a) Major myofibril length after one day of growth is similar for NRVMs plated on either 100 or 400 kPa of micropost or flat substrata. (b) Major myofibril length after three days of growth is statistically significant over time but not significant for the micropost or flat substrates. (c) NRVM surface area growth was also found to not be statistically different relative to substrate surface plated upon but relative to time. (d) Paxillin localized more around 100 kPa compared to 400 kPa microposts after three days of growth (p=0.08). (a,b) N=15 cells per condition from 3 experiments; (c, d) n=7=8 cells per condition from 3 experiments. Statistical Significance: ** p<0.01; *** p<0.0001.