Table 3.
VWF laboratory values for type 2 VWD subjects
| Type 2A (n = 43) | Type 2B (n = 19) | Type 2M (n = 15) | Type 2N (n = 8) | |||||
|---|---|---|---|---|---|---|---|---|
| Median | IQR | Median | IQR | Median | IQR | Median | IQR | |
| VWF:Ag | 27 | 21-35 | 37 | 22-44 | 43 | 25-64 | 75 | 55-94 |
| VWF:RCo | 5 | 5-14 | 14 | 12-22 | 17 | 11-32 | 87 | 52-126 |
| VWF:RCo/VWF:Ag ratio | 0.29 | 0.19-0.47 | 0.47 | 0.32-0.67 | 0.45 | 0.39-0.55 | 1.08 | 1.01-1.29 |
| VWF:CB3 | 8 | 4-24 | 12 | 6-22 | 43 | 27-69 | 95 | 59-108 |
| VWF:CB3/VWF:Ag ratio | 0.31 | 0.17-0.70 | 0.37 | 0.26-0.56 | 1.08 | 0.97-1.11 | 1.12 | 1.09-1.20 |
| VWF:CB4 | 13 | 8-22 | 16 | 8-26 | 23 | 14-45 | 84 | 54-98 |
| VWF:CB4/VWF:Ag ratio | 0.50 | 0.40-0.60 | 0.52 | 0.36-0.60 | 0.67 | 0.48-0.89 | 1.06 | 0.78-1.24 |
| Bleeding score | 8 | 4-11 | 10 | 4-13 | 11 | 4-12 | 8.5 | 2.5-16.5 |
IQR, interquartile range.
Data are given in IU/dL with the exception of VWF:CB4, which was normalized to an international standard and is given in U/dL. For subjects with values below the lower limit of detection for each assay, an arbitrary value was assigned for calculation purposes (5 IU/dL for VWF:RCo <10 IU/dL, 0.5 IU/dL for VWF:CB3 <1 IU/dL, and 0.8 U/dL for VWF:CB4 <1.6 U/dL).