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. 2015 Mar 29;150(3):547–557. doi: 10.1007/s10549-015-3352-0

Table 1.

Clinical and pathological characteristics of metastatic breast cancer patients

N %
Age at diagnosis, years
 <50 146 55.5
 >50 117 44.5
Lymph node status
 Negative 54 34.4
 1–3 Positive 52 33.1
 >3 Positive 51 32.5
Histology
 Ductal 231 88.2
 Lobular 20 7.6
 Other 11 4.2
Tumour grade
 1 23 9.1
 2 134 53.0
 3 96 37.9
Tumour size
 0–2 cm 63 28.5
 2–5 cm 131 59.3
 >5 cm 27 12.2
Tumour subtype
 ER(−) HER2(−) 59 27.6
 ER(+) HER2(−) Ki67high 75 35.0
 ER(+) HER2(−) Ki67low 27 12.6
 ER(+) HER2(+) 28 13.1
 ER(−) HER2(+) 25 11.7
Time to distant metastasisa
 Early 194 75.8
 Late 62 24.2
Multiple metastasis sites at first presentation
 No 160 62.7
 Yes 95 37.3
Multiple metastasis sites during follow-up
No 50 19.6
Yes 205 80.4

CT chemotherapy, HT hormonal therapy, ER oestrogen receptor, PR progesterone receptor; HER2 human epidermal growth factor receptor

aCut-off point 5 years