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. 2015 Mar 29;150(3):547–557. doi: 10.1007/s10549-015-3352-0

Table 4.

Correlation between tumour characteristics and time to distant metastasis

Characteristics Metastasis timeline
< 5 years >5 years p
N % N %
Tumour size
 <2 cm 37 21.8 27 42.9 0.001
 ≥2 133 78.2 36 57.1
Tumour grade
 1 17 8.5 7 10.6
 2 99 49.3 42 63.6 0.056
 3 85 42.3 17 25.8
ER
 Negative 73 37.4 10 15.2
 Positive 122 62.6 56 84.8 0.001
PR
 Negative 83 41.9 12 17.6
 Positive 115 58.1 56 82.4 <0.001
Tumour subtype
 ER(−) HER2(−) 52 30.8 7 13.5
 ER(+) HER2(−) Ki67high 50 29.6 25 48.1
 ER(+) HER2(−) Ki67low 17 10.1 9 17.3 0.003
 ER(+) HER2(+) 29 17.2 8 15.4
 ER(−) HER2(+) 21 12.4 3 5.8

ER oestrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor