Table 1. Comparison of ADReCS to some typical ADR databases.
Resources | ADReCS v1.2 | MedDRA 17.0 | WHO-ART (Jan 2014) | SIDER2 | PROTECT ADR database |
---|---|---|---|---|---|
Hierarchical structure | Four levels | Five levels | Four levels | N/A | N/A |
ID of ADR terma | 10.01.03.002 | 10001738b | 1058 001c | N/A | N/A |
Definition of ADR | Yes | N/A | N/A | Yes | N/A |
Number of PTs | 4906 | 20 559 | 2178 | 4192 | 5676 |
Number of synonyms/LLTs | 34 796 | 72 637 | 5813 | >6000 | N/A |
Number of drugs | 1353 | N/A | N/A | 996 | 677 |
Number of drug–ADR pairs | 134 022 | N/A | N/A | 99 423 | 46 687 |
N/A = Not available
aUsing ‘Allergy’ as an example.
bMedDRA codes are assigned in alphabetical order starting with 10000001.
cWHO-ART codes are assigned by combining the high-level term ID (e.g. 1058) with a sequential number of ADR term (starting from 001).