Table 1. Statistics for the TTSMI database.
TTS search criteria | Number of TTSs (thousands) | Number of pGFA-TTSs (thousands) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
%G | pyr | #GpGpG | with chromatin accessibility | with chromatin state | with TFBS (ChIP-seq) | with CpG Island | with G4 | with non-B DNA | with TFBS (Motif) | with evolutionarily conserved regions | with repeat elements | with SNPs (138) | |
<40 | 0 | <4 | 2349 | 119 | 506 | 236 | 2 | 57 | 2003 | 13 | 66 | 2117 | 1331 |
<40 | 1 | <4 | 9259 | 820 | 2043 | 1134 | 17 | 89 | 5164 | 138 | 503 | 6313 | 4166 |
≥40 | 0 | <4 | 6095 | 798 | 1661 | 1042 | 28 | 1178 | 5072 | 48 | 192 | 5483 | 2993 |
≥40 | 1 | <4 | 17047 | 3579 | 5238 | 3417 | 195 | 2088 | 9136 | 337 | 971 | 11 287 | 7086 |
≥40 | 0 | ≥4 | 634 | 137 | 243 | 103 | 6 | 588 | 628 | 6 | 23 | 617 | 357 |
≥40 | 1 | ≥4 | 930 | 270 | 350 | 198 | 26 | 838 | 894 | 25 | 62 | 809 | 506 |
%G, guanine content; pyr, #pyrimidine interruptions; #GpGpG, number of three consecutive guanines; TTSs, triplex target DNA sites; pGFA-TTSs, potential gene function-associated TTSs; G4, G-quadruplex.