Table 5.
Wound healing phases on day 4 and 8 in the circular excision wound model. HE and MT stained sections on day 4 and 8 were scored as none (−), mild (+), moderate (++) and severe (+++) for epidermal and/or dermal re-modeling. I: inflammation phase; P: proliferation phase; R: re-modeling phase. NT: non-treatment control; Water: vehicle control; CNFs: chitin nanofibrils treatment; SDACNFs: superficially deacetylated chitin nanofibrils treatment; CSNFs: chitosan nanofibrils treatment.
| I | P | R | |
|---|---|---|---|
| Day 4 | |||
| NT | +++ | + | − |
| Water | +++ | + | − |
| Chitin | ++/+++ | ++ | − |
| CNF | ++/+++ | ++ | − |
| SDACNF | ++ | ++ | + |
| CSNF | ++/+++ | ++ | − |
| Day 8 | |||
| NT | ++ | + | + |
| Water | ++ | ++ | + |
| Chitin | ++ | ++ | −/+ |
| CNF | + | ++ | ++ |
| SDACNF | + | +++ | +++ |
| CSNF | ++/+++ | ++/+++ | + |