Table 5. Pooled weighted mean estimates of hemodynamic outcomes.
| Hemodynamic outcome | n | N | Weighted pooled proportion or estimate (95% CI) | Heterogeneity |
|
|---|---|---|---|---|---|
| I2 (%) | P value | ||||
| Mean gradient | |||||
| Mean gradient (discharge) | 654 | 8 | 11.128 (9.831,12.425) | 94 | <0.001 |
| Mean gradient (6 mo) | 529 | 5 | 9.004 (8.697,9.311) | 0 | 0.663 |
| Mean gradient (12 mo) | 579 | 6 | 9.644 (8.703,10.586) | 86 | <0.001 |
| Peak gradient | |||||
| Peak gradient (discharge) | 529 | 5 | 19.61 (16.54,22.681) | 95 | <0.001 |
| Peak gradient (6 mo) | 529 | 5 | 17.797 (16.046,19.547) | 86 | <0.001 |
| Peak gradient (12 mo) | 528 | 5 | 17.286 (16.136,18.436) | 69 | 0.007 |
| Effective orifice area | |||||
| Effective orifice area (discharge) | 579 | 6 | 1.772 (1.554,1.990) | 98 | <0.001 |
| Effective orifice area (6 mo) | 529 | 5 | 1.745 (1.499,1.991) | 97 | <0.001 |
| Effective orifice area (12 mo) | 577 | 6 | 1.731 (1.548,1.914) | 97 | <0.001 |
n, number of patients; N, number of studies; CI, confidence interval.